A new research suggests that couples can get to know about their odds of successful IVF or in vitro fertilization through a newly created calculator.
Traditionally, doctors hold back on providing couples with an estimation regarding the success of undergoing IVF until they have completed one cycle of the procedure. A single cycle allows clinicians to analyze the quality of the sperm, eggs, and embryos. They also get to know about weight, age, and other medical conditions.
However, this can change through the use of a newly created pre-treatment calculator for IVF. This calculator can provide people with an estimate regarding their rates of success even before the completion of the first IVF cycle. According to the lead author of the study, Dr. David McLernon, adjustments can be made by doctors based on what they observe through the calculator. Dr. David McLernon is from the University of Aberdeen, UK.
He also added that as far as he knows, women aren’t interested in undergoing the first IVF cycle to see their chances of success for future cycles. Their aim has to do with being successful in the very first attempt.
For conducting the current research, data on 113,873 women was examined by the team. The data included 184,269 complete cycles of IVF. In the current data, 29% women were able to have a baby after the completion of their first cycle while it took six cycles for 43% of women to have a child. The results of the current study were published in the British Journal of Medicine.
Age plays a role in determining the pre-treatment odds of IVF success. A success rate of 66% was observed in women aged 31 years before their first IVF cycle compared to women who were 37 years of age. The years of infertility before IVF also played a role in chances of successful treatment. Couples facing three years of infertility had a 9% higher chance of success compared to couples with six years of infertility.
Factors including the age of women, the number of eggs that were retrieved in a cycle, development of embryos before transfer, whether embryos were frozen, etc. influenced the rate of success once the IVF began. The results of the study found that the odds of success increased with up to 13 eggs. However, the rate might decrease with more eggs as their quality might be reduced too.
Through the combination of all such factors, the team of researchers was able to calculate that before IVF treatment, a 46% chance of success after one cycle is experienced by a woman (30 years of age) with two years of infertility. The rate increased to 79% over three IVF cycles.
The authors of the study also caution that the created calculator can’t address every single factor that might have an influence on success rate. It may be possible that a factor that isn’t part of the new calculator might play a role in influencing the odds of success.
While the medical community is welcoming the creation of the new calculator, the researchers note that some women might need to undergo a few IVF cycles even if the calculator shows a high success rate.