Scientists have discovered that people who are suffering from both obesity and Type-II diabetes experience double the risk of developing liver cancer. The results showed that the risk factor increased by 2.61 times in people who happened to have a very high BMI (body mass index), Type-II diabetes and an increased waist circumference.
The recent study suggests that the risk of liver cancer keeps on increasing with the increase in a person’s BMI. The risk factor increased by 8% for very 5cm increase in a person’s waistline. Coming to the sexes, an increase in liver cancer risk by 38% in men and 25% in women was seen with each 5 kg per meters squared increase in a person’s BMI.
According to the author of the study, Dr. Peter Campbell, the strategic director of digestive system cancer research at the American Cancer Society, the rates of liver cancer has more or less tripled since the mid-1970’s in the U.S. The prognosis for all of the patients that are diagnosed with such a disease isn’t hopeful either.
The rates of liver cancer have also increased in the U.K. even though the disease was very uncommon just a few decades ago. The reason for such an increase could be due to the higher rates of obesity and consumption of alcohol.
In order to conduct the current study, published in Cancer Research, Dr. Campbell and his team of researchers observed data from 1.57 million adults. All of them were participants in 14 different studies based in the U.S.
All of the participants were asked to complete questionnaires with regards to their weight, height, tobacco use, intake of alcohol, and some other factors that have been studied to be potentially linked to the risk of developing cancer. None of the participants were suffering from cancer when they enrolled in the study.
A total of 6.5% of the participants had Type-II diabetes and with time a total of 2,162 ended up developing liver cancer. In order to observe the relative risks of cancer the researchers compared the rate of liver cancer to participants were and weren’t suffering from diabetes and obesity.
The results showed that there was an association present between liver cancer and people suffering from obesity and Type-II diabetes. All three of these diseases related to a dysfunction in a person’s metabolism. The results add support behind liver cancer to be included in the list of cancers that are associated with obesity. The current results are similar to other previously conducted research that indicate an increased risk of liver cancer being linked to diabetes and being overweight. The results also show that liver cancer isn’t a disease that is specifically related to too much alcohol consumption or an infection of viral hepatitis.
Just in the U.S., about eight in every 100,000 adults suffer from liver cancer per year. The risk is doubled in people who are already suffering from Type-II diabetes compared to people who aren’t.
The co-author of the current study also shared her opinion. Dr Katherine A. McGlynn, who is also a senior investigator in the Metabolic Epidemiology Branch at the National Cancer Institute, said that if one was to look at the results from the perspective of public health they happen to be very important because health conditions such as diabetes and obesity tend to be very common in the global population.
The results also provide people with another reason for maintaining a healthy lifestyle.